Novel classification of allergic disorders

Novel classification of allergic disorders

The European Academy of Allergy and Clinical Immunology (EAACI) is proud to announce the release of a new classification system for allergic disorders.

Traditionally, allergic diseases have been categorized based on symptoms and organ dysfunction. However, in this era of patient-tailored treatments and precision medicine, a long-awaited shift has occurred. The new classification is founded on disease mechanisms, ushering in a new era of targeted and personalized disease management.

Key Highlights:

  • A Paradigm Shift: The new classification fundamentally changes how we perceive and approach allergic diseases, focusing on immune-competent cells, tissue changes, microbial infections, and genetic and epigenetic influences that impact the protective epithelial barrier of the skin, respiratory tract, and gut.
  • Precision Medicine: With the exponential growth of precision diagnostic tools, including omic technology, molecular diagnostics, imaging, and advanced genetic and epigenetic editing, this nuanced approach moves us closer to precision and personalized medicine.
  • Consensus and Dissemination: Achieving a general consensus and rapid dissemination of this new nomenclature is crucial to advancing the management of immune-mediated diseases.
  • Cultural Change: This shift will lead to novel concepts in diagnostic tools, improved therapies, and disease management. It will guide future research toward innovative strategies for patient care.
  • Promising Therapies: The new nomenclature paves the way for pinpoint targeted immune-based therapies, including biologicals, allergen immunotherapy, and strategies to alter the composition of the human microbiome, among others.
  • A Better Way Forward: We believe that this new nomenclature will empower healthcare professionals and patients to find more effective ways to manage and potentially even cure allergic diseases.

We invite you to explore the full details of this groundbreaking development in the position paper published online in Allergy. The future of allergy science and patient care is brighter than ever, thanks to all the authors for this significant step forward!

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