EAACI Biologicals Guidelines

EAACI Biologicals Guidelines

Omalizumab for the treatment of chronic spontaneous urticaria in children and in adults

Chronic spontaneous urticaria (CSU) imposes a significant burden on patients, families and healthcare systems. Management is difficult, due to disease heterogeneity and insufficient efficacy of classical drugs such as H1R-antihistamines. Better understanding of the mechanisms has enabled a stratified approach to the management of CSU, supporting the use of targeted treatment with omalizumab. However, many practical issues including selection of responders, the definition of response, strategies to enhance the responder rate, the duration of treatment and its regimen (in the clinic or home-based) and its cost effectiveness still require further clarification.

The EAACI Guidelines on the use of omalizumab in CSU follow the GRADE approach in formulating recommendations for each outcome. In addition, future therapeutic approaches and perspectives as well as research priorities are discussed.

As a significant step in the creation of the EAACI Biologicals Guidelines, chapters are now being made available until 00:00 on 9 June 2021 for public review and commentary.

After feedback has been gathered, all the chapters, will be revised before publishing in autumn 2021.

We hereby invite all interested individuals, societies and stakeholders to study the documents and provide their valuable input via the dedicated online platform.

On behalf of EAACI, I wish to thank you very much for your valuable contribution to improve these important guidelines.  

Marek Jutel
EAACI President
Corresponding Author

Ioana Agache
EAACI Past President
Corresponding Author

Oscar Palomares
EAACI IG Representative
Corresponding Author

 

01. EAACI Biologicals Guidelines

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Last updated 26 May 2021
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